Ion‐molecule reactions of 2‐methoxyethanol with some amines, carboxylic acids and amino acids under chemical ionization conditions

Abstract

2-Methoxyethanol chemical ionization of amines, carboxylic acids and amino acids has been found to produce numerous adduct ions. The most intense adduct ions for amines are [M + H]+ and [M + 77]+, for carboxylic acids [M + 27]+, [M + 59]+ and [M + 77]+, and for amino acids [M + H]+, [M + 13]+, [M + 27]+ and [M + 77]+. Either the adduct ion [M + H]+ or [M + 77]+ was the most abundant ion found for amino acids. The proton affinities of amino acids are noticed to control the formation of the [M + H]+ and [M + 77]+ ions. The relative abundance of [M + 13]+ and [M + 27]+ ions varied for different amino acids being most intense for phenylalanine and aspartic acid. Copyright © 1999 John Wiley & Sons, Ltd.