Ionizing diagnostic radiation exposure in patients with Crohn's disease: A retrospective study in a medium hospital and its predictive factors

Abstract

Abstract Introduction It is estimated that diagnostic medical radiation exposure may be responsible for 0.5–2% of cancers worldwide. Because of the relapsing course of Crohn's disease (CD), these patients usually require multiple ionising radiation test. Objective Stimulating the total cumulative effective dose received by our CD patients and identifying the risk factors associated with the exposure to a cumulative effective dose due to the disease (CEED) ≥50 mSv. Materials and methods Retrospective cohort study (2001–2014). Population: patients with CD. Risk dose ≥50 mSv. For calculating de cumulative effective dose and the CEED, all the ionising test done were taken. For identifying predictive factors for receiving a CEDD ≥50 mSv, an univariate and a multivariate logistic regression analyses were performed using a ≥50 mSv dose as dependent variable. Results Of the 267 patients analysed the 24.6% of them received a cumulative effective dose ≥50 mSv and the 15.2% a CEED ≥50 mSv. In the multivariate analysis, the following variables were identified as independent predictors associated with a CEDD ≥50 mSv: major surgery (OR = 2.1; IC95% [1.1–3.8]; p = 0.019) and severity (OR = 20.6; IC95% [4.5–94.8]; p Conclusions Patients with CD are more at risk of receiving risk CEED, so it would be advisable to monitor the cumulative effective dose received to anticipate our intervention in order to avoid reaching that dose. The ultrasounds and abdominal resonance enterography are alternatives in these cases, although their accessibility is limited in some centres.