Abstract

Ion Release and Bactericidal Activity of Ag /Tryptophan and Ag/Cu/Tryptophan Complexes in the Structure of Cotton Tissue

Highlights

  • This article continues a series of publications devoted to the production and study of bactericidal tissues modified with nanoparticles of silver (Ag NPs), copper (Cu NPs) and their bimetallic compositions (BMNPs) (Ag/Cu NPs)

  • The work quantitatively studied the leaching into water of Ag and Cu ions, from Ag and Ag/Cu nanoparticles (NPs) fixed on the surface of bactericidal tissues –cotton fabrics in the form of complexes with tryptophan (Trp) molecules

  • To prevent toxic side effects of metal NPs on the body, simultaneously biomolecules or drugs are used for complex therapy of infectious-inflammatory diseases, and the most commonly used is the amino acid Trp, Silver nanoparticles prepared with tryptophan were found to effectively prevent the formation and kill bacteria in established biofilm structures and may be useful for the prevention and treatment of biofilm-related infections [14-26 and references therein]

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Summary

Introduction

This article continues a series of publications devoted to the production and study of bactericidal tissues modified with nanoparticles of silver (Ag NPs), copper (Cu NPs) and their bimetallic compositions (BMNPs) (Ag/Cu NPs). The work quantitatively studied the leaching into water of Ag and Cu ions, from Ag and Ag/Cu nanoparticles (NPs) fixed on the surface of bactericidal tissues –cotton fabrics (cf) in the form of complexes with tryptophan (Trp) molecules. The effect of the modification of Ag/Cu NPs in cotton tissues by Trp on their bactericidal activity is studied.

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Conclusion

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