Ion mobility spectrometry and ion mobility spectrometry/mass spectrometric characterization of dimenhydrinate.

Abstract

Positive and negative ion mobility spectra of dimenhydrinate are presented, and the calculated reduced mobility (K0) values for the most significant peaks are reported. Mass identification of the ionic species associated with the peaks in the ion mobility spectra was achieved by interfacing the ion mobility spectrometer to a mass spectrometer. The application of ion mobility spectrometry to the detection of dimenhydrinate and other drug residues on the hands of patients admitted to hospital with drug overdose is also discussed.