Abstract
In recent years various ionic channels have been reconstituted in planar lipid bilayers by which rigorous analysis of the electrical behavior of single ionic channels can be made. I have reviewed, in the first half of this article, practical techniques for forming planar bilayers and for incorporating channels into them. The second half deals with a structural analysis of the ion conducting pathway of the reconstituted K+ channel from sarcoplasmic reticulum solely by measuring its electrical properties. The electrical analysis of channel structure should be a promissing approach to bridge the gap between the electrical property and the molecular structure of channel proteins in lipid bilayers.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
