Iodine-prophylaxis in Adolescents

Abstract

The aim of the study is to estimate a current state of iodine deficiency problem and necessity group (individual) iodine prophylaxis in adolescent living in iodine deficiency regions. Materials and methods. One-stage epidemiological survey was carried on in two cities: Smolensk and Kazan. There were examined 420 children at the age of 14–16 years. Research methods included: clinical survey, an estimation physical developments estimation (height and weight measurement), ultrasound examination of a thyroid, urinary iodine concentration(UI) measuring, analysis of thyrotropin (TSH) and thyroperoxidase autoantibody. The main results. Prevalence of a diffuse goiter in both regions was approximately equal and corresponded to mild iodine deficiency (10.5% in Smolensk and 8% in Kazan). At the same time, the mean of thyroid volume was significantly higher in a group of teenagers surveyed in Smolensk. Also we revealed that prevalence of nodule goiter is more frequent in Smolensk in than in Kazan. UI in schoolchildren in Smolensk corresponds to mild iodine deficiency (median UI is 61 μg/L). UI indicators in Kazan vice versa correspond to normal level of iodine consumption (median UI is 117.5 μg/L). Essential distinction of iodine sufficiency level has direct relation with iodine prophylactic measures in regions. Data in adolescents in Smolensk reveal insufficient iodine consumption and possible related risk of iodine deficiency disorders development. Conclusion. The obtained results show the necessity of group iodine prophylactic measures in adolescents who livein iodine deficiency regions with any severity level.