Iodine nutritional status and thyroglobulin in adult women of Dali City, Yunnan Province

Abstract

Objective To study the urinary iodine and serum thyroid stimulating hormone (TSH) and thyroglobulin (Tg) levels in adult women (pregnant women, lactating women, childbearing age women) in Dali City, Yunnan Province, and to explore the feasibility of TSH and Tg as indicators for iodine nutrition evaluation in pregnant women. Methods From July to December 2014, from the five districts of east, west, south, north and middle district of Dali City, Yunnan Province, one township (town) was selected, and 20 pregnant women in the early, middle and late stages, respectively, 20 lactating women, 20 childbearing age women were selected from each township (town), collected urine and blood samples, and urinary iodine, serum TSH and Tg levels were detected. Results The medians urinary iodine (MUI) in different populations were 136.85 μg/L for pregnant women (n = 356), 102.63 μg/L for lactating women (n = 111), 166.21 μg/L for childbearing age women (n = 98). The medians TSH in pregnant women (n = 368), lactating women (n = 112) and childbearing age women (n = 96) were 1.995, 2.345 and 2.565 mU/L, respectively, the difference between the different populations was statistically significant(χ2 = 16.128, P 0.05). A total of 120, 126, and 122 cases of pregnant women in the early, middle, and late stages were investigated. The medians TSH of early, middle and late pregnancy were 1.850, 2.030 and 2.235 mU/L, respectively, the difference between the different stages of pregnancy was statistically significant(χ2 = 6.970, P 0.05). Conclusions Tg levels are stable in the different stages of pregnancy women and it can be considered as an indicator of iodine nutrition evaluation in pregnant women. Key words: Iodine; Pregnant; Thyroglobulin