Abstract

AbstractAn environmentally benign, efficient, practically applicable and C(sp3)−H functionalization of primary amines for the synthesis of highly substituted oxazoles from easily available internal alkynes was developed. This synthesis is toxic chemicals, transition‐metal free as well as mild and regioselective. This one‐pot methodology with broad substrate scope unlocks a green avenue for the synthesis of highly functionalized oxazole derivatives with excellent yields.

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