Abstract
Objective: Iodine deficiency is a commonly seen problem and associated with pregnancy complications. In this study, we aimed to evaluate urinary iodine status in pregnant women with hyperemesis gravidarumStudy Design: A total of 121 women experiencing singleton pregnancies between 6 and 18 weeks of gestation were included in the study. The participants were divided into two groups; group 1 comprised 81 healthy pregnant women, and group 2 comprised 40 pregnant women with Hyperemesis Gravidarum.Results: Urinary iodine levels were found to be significantly higher in healthy pregnant women than women with Hyperemesis Gravidarum (p=0.008). Urinary iodine was significantly correlated with the urinary ketone (r= -0.252, p=0.005) and FT3 (r= -0.190, p=0.037).Conclusion: In pregnant women with hyperemesis gravidarum, oxidative stress was increased, urinary iodine levels were significantly low and negatively correlated with disease severity. Thus, ıodine replacement might be essential to prevent pregnancy complications.
Highlights
Urinary iodine levels were found to be significantly higher in healthy pregnant women than women with Hyperemesis Gravidarum (p=0.008)
Hyperemesis gravidarum (HEG) is a condition that occurs in 0.3–2.0% of pregnancies and which is characterized by severe nausea and vomiting accompanied by weight loss or dehydration, causing a decrease in nutrient antioxidants and a loss of crucial elements and minerals [1]
We evaluated the relationship between oxidative stress and HEG by measuring serum GGT levels
Summary
Hyperemesis gravidarum (HEG) is a condition that occurs in 0.3–2.0% of pregnancies and which is characterized by severe nausea and vomiting accompanied by weight loss or dehydration, causing a decrease in nutrient antioxidants and a loss of crucial elements and minerals [1]. Quick Response Code: Access this article online. How to cite this article: Arslanca SB. Iodine Levels in Pregnant Women with Hyperemesis Gravidarum Gynecol Obstet Reprod Med 2021;27(1): nancy [2]. It is associated with maternal weight loss and electrolyte imbalance and causes adverse perinatal outcomes [3], including lower birth weight, preterm delivery, and congenital anomalies of the central nervous system [4]
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