Abstract
Screening for hypothyroidism shows that use of PVP-Iodine as desinfectant may cause TSH elevations in the newborns. In order to examine if these elevations are a pathological symptom,we determined TSH,T4,T3 and fT4 and the iodine excretion on days 1,3 and 5 in 23 mothers and their newborns after use of PVP-I.for different periods of time before delivery (7-14o h.mean 25h). Results are shown below (mean values, mother = M, newborn = NB, day = D). Four NB had elevated TSH levels, but T4, T3 and free T4 were normal. Two other NB showed hyperthyroid serum levels on days 3 and 5.None of the mothers had TSH elevations or other impairment of thyroid function. No correlation was found between duration of PVP-I. use and iodine levels, nor between iodine levels of mothers and newborns.Finally, there was no correlation between iodine levels and impairment of newborn thyroid function. We conclude that the newborn thyroid is very sensitive towards iodine excess,but we don't think that these infants need treatment.
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