Abstract
AbstractA double C−H functionalization of cyclopentenedione with benzamidine hydrochloride catalyzed by iodine has been disclosed for synthesizing fused imidazole derivatives. This methodology leads to a variety of fused imidazole derivatives and requires a sub‐stoichiometric amount of iodine as a catalyst and aqueous tert‐butyl hydroperoxide (TBHP) as an oxidant. This reaction involves a double‐cross dehydrogenative coupling (CDC) of 1,3‐cyclopentenedione and benzamidine hydrochloride to form two C−N bonds in a consecutive manner within short reaction time. A plausible mechanism has been proposed based on the mass spectrometric analysis.magnified image
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
