Abstract
Iodine-129 ( t 1 2 = 1.57 × 10 7y ) was used as a protein label for the measurement of the turnover rate of albumin in two human subjects. Plasma samples were assayed for 129I using destructive neutron activation analysis. The experiment entailed an estimated radiation dose of 0.2 μSv to the total body of the subjects. The turnover parameters showed reasonable agreement with literature values. When in a rabbit the catabolism of ( 129I + 131I)-labeled autologous albumin was followed, the results obtained with both labels agreed well.
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More From: International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology
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