Abstract
1. Flight had no significant effect on the levels of c-AMP of c-GMP in the flight muscles of Locusta migratoria. 2. Injections of 0.01 or 0.1 corpus cardiacum equivalents into the abdominal cavity did not elicit any effect on cyclic nucleotide levels either. 3. Injection of A23187 resulted in a decrease of the c-AMP level, but not the c-GMP level. 4. Marked increase of the c-AMP level was found to occur in the flight muscles after injection of octopamine, whereas c-GMP level was not influenced. 5. It is concluded that octopamine acts on locust flight muscles through c-AMP mediated activation of glycogen phosphorylase.
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