Abstract
Propranolol has emerged as a new treatment option for infantile hemangiomas. We describe a 20-month-old boy with a large right parotid hemangioma diagnosed at the age of 37 days. Starting at the age of 2.5 months, he received oral propranolol for 6.5 months. Although the mass regressed, it recurred when propranolol was discontinued. He was successfully retreated at the age of 11 months with propranolol for another 5.5 months without further recurrences. Treatment was tolerated well. Our paper and a review of the literature demonstrate that propranolol appears to be safe and effective for symptomatic infantile parotid gland hemangiomas.
Highlights
Parotid hemangiomas (PHs) are among the most common causes of facial asymmetry in infants [1, 2]
PHs are more common in females [1, 4,5,6,7]
We present an infant boy with a large PH who demonstrated substantial involution of the lesion after administration of oral propranolol and review the relevant literature
Summary
Parotid hemangiomas (PHs) are among the most common causes of facial asymmetry in infants [1, 2]. PHs account for >50% of salivary tumors [3, 4]. The majority of them are already present at birth, while 90% appear within the first year of life [4]. PHs are more common in females [1, 4,5,6,7]. Cutaneous involvement of the overlying skin is found in >50% of the cases [2]. We present an infant boy with a large PH who demonstrated substantial involution of the lesion after administration of oral propranolol and review the relevant literature
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