Abstract

In India, the prevalence of diabetes mellitus is on increase and needs to be addressed appropriately. In this study area, herbal remedies are considered convenient for management of type 2 diabetes with postprandial hyperglycemia due to their traditional acceptability and availability, low costs and lesser side effects. The present study involves screening of LEAF EXTRACTS OF PITHECELLOBIUM DULCE (Roxb.) Benth for anti-diabetic activity on alloxan induced diabetic Swiss albino mice using glibenclamide as standard. Ethanol and aqueous extracts (200mg/kg b.w.) of leaves of PITHECELLOBIUM DULCE (Roxb.) Benth were screened. Among extracts , alcoholic extracts leaves of PITHECELLOBIUM DULCE (Roxb.) Benth shown more significant (p<0.01) reduction in blood glucose level in alloxan induced diabetic Swiss albino mice when compared to aqueous . Keywords: Anti diabetic , blood glucose , glibenclamide , Swiss albino mice

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