Abstract

Haemodynamic forces within the carotid artery (CA) are well understood to be a key player in the initiation and progression of vascular disease and detailed measurements of the interaction between the local flow field and wall shear stress (WSS) within the CA facilitates a better understanding of local haemodynamics. Most experimental approaches, including in-vivo measurements, provide insufficient spatial or temporal resolution needed for a detailed quantitative assessment of CA haemodynamics. In the present study, we present a three-dimensional tomographic Particle Image Velocimetry (Tomo-PIV) measurement in a patient specific CA flow phantom. The CA model is reconstructed from medical image data and reproduced in a 3 times scaled transparent silicone phantom. The Tomo-PIV measurements utilize an arrangement of four digital CCD cameras and a volumetric laser light illumination of suspended tracer particles in an aqueous glycerin solution. The full three-dimensional and three-component (3D3C) velocity field within the CA is determined by tomographic reconstruction and subsequent crosscorrelation of the recoded particle images and the subsequent WSS distribution is derived from the experimental 3D velocity field.

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