Abstract
In this study antimicrobial activity of ethanolic extract of Citrullus colocynthis, Ekebergia capensis and Echium rauwolfii used in Sudanese folk medicine was detected against five standards bacterial strain viz Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Pseudomonas aeruginosa (ATCC 27853), Klebsiella pneumonia (ATCC 53657), using well-diffusion agar diffusion method. The drude extract of C. collosynthis showed good activity against most organisms (25-12) in different concentrations. ethanolic extract of E. capensis showed high activity in most microbial (28-11) in different concentrations but no activity against E. coli and K. pneumoniae in concentration (6.2). The crude extract of E. rauwolfii showed good activity against all microorganisms (26-12) in all concentrations used, except in concentration (6.2) there was no activity against E. coli. Phytochemical investigation of secondary metabolic compounds such as alkaloids, tannins, glycosides, saponins, turbines, flavonoids, is found in these plants.
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