Abstract
Summary Essential oils from many plants are known to possess antifungal activity, but only limited information exists about activity towards human and animal fungal pathogens. The in vitro sensitivity of nine clinical isolates of Trichophyton equinum to tea tree oil (TTO) was evaluated by a microdilution test. As the quality and the chemical composition of the commercial essential oils of Melaleuca alternifolia are extremely variable, all the essential oil samples were analyzed by gas-chromatography mass spectrometry (GC-MS) before being used for the assays. All the oil samples showed minimum inhibitory concentrations minimum inhibitory concentrations (MICs) of 2.5%, and 4% yielded a fungicidal effect. Compared to other results reported in literature, the present findings indicate a lesser in vitro susceptibility of T. equinum, to TTO. This fact could be explained by different testing conditions, namely medium and diluent employed.
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