Abstract

experimental biomedical study was carried out at Omdurman Maternal Hospital, Saudi Maternal Hospital and AlzaiemAlazhari University during the period from September to December 2021. 30 Candida species, of them 17 isolated from urine samples and 13 from vaginal swabs were included in this study. Antifungal activity was performed usingcup plate method using different concentrations of plant extraction (100%, 50% and 25%) and fluconazole(10μg). The statistical analysis was performed using SPSS version 20. Results: the results showed significant increase in antifungal activity with increase in Ziziphusmauritianaconcentration, while fluconazole showed best antifungal activity.However, the fungicidal concentration showed that Ziziphusmauritiana methanol extracts was able to inhibit Candia SPPs rather than C. albicans.

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