Abstract
Paper substrates are becoming a sustainable material for various applications related to the rapid monitoring of different analytes. Capillary forces within the paper's pores can be used to manipulate the transport of different chemicals and target analytes. We have used paper strips to detect E. coli in contaminated water. An enzymatic reaction is conducted on the paper substrate, and it provides a colour change in the presence of water-borne pathogens. Like pathogens, another growing concern is the amount of pesticides in water. We have developed a novel device, “Dip-and-Fold”, which detects pesticides, such as carbamates and organophosphates, via Ellman’s acetylcholinesterase (AChE) inhibition method. This technology is user-friendly and does not need any extra steps for adding reagents. Towards the fight against COVID-19, a sustainable technology based on a paper strip with conjugated nanoparticles and aptamers is discussed. Finally, such lateral flow assays can be used for detection of tuberculosis in limited resource communities.
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