Abstract

This talk will highlight the research and development efforts of my team towards the personalized diagnostic breathalyzer to be used for the detection and monitoring of diseases or metabolic malfunctions, both in humans and in livestock. Based on the principle of selective chemosensing, nanostructured, gas-selective probes have been developed which detect disease-signaling biomarkers in a single exhale. Such probes include: NO sensor for asthma monitoring; acetone sensor for the control of treatment in diabetics; ammonia for determining the end-point in hemodialysis, etc. These sensing probes, whether individually or in arrays, constitute components of sensory systems that are inexpensive, handheld, wireless, and low power. The pathway and timeline from lab-based prototyping to industrial scale manufacturing of this technology are also discussed here.

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