Abstract
New biomarkers are always needed for the fast and early diagnosis of gastric cancer. Lately, maspin was used for diagnosis of gastric cancer. Most of the standard methods are only used for qualitative assay of maspin. Its quantification is very important for the correct diagnosis of gastric cancer. 2D disposable sensors as well as 3D microsensors based on graphene modified with nanoparticles were proposed for the fast screening tests – based on molecular recognition and quantification of maspin in biological samples such as whole blood, tumor tissue, saliva, and urine. High sensitivity and low limits of determinations were recorded for the assay of maspin. High reliability was obtained for the assay of maspin in biological samples.
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