Abstract
Dr. Biesman has written an overview of the nonanimal stabilized hyaluronic acid (NASHA) fillers. Restylane is approved by the Food and Drug Administration as a dermal filler for the correction of soft tissue contour deficiencies. Streptococcal bacterial fermentation is used to produce the Restylane. Marketed in the United States and Canada by Medicis, Restylane is a medium viscosity glycosaminogylcan, and very versatile as a mid to deep dermal filler. An expanded spectrum of NASHA fillers is awaited to be able to fill more superficial dermal lines as well as to use more deeply as a facial contouring substance.
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