Abstract

In the mid-90s, the potential of cardiac cine-magnetic resonance imaging (MRI) in quantitative and observer-independent assessment of myocardial function were apparent. Initially, assessment of left ventricular function in ischemic heart disease was essentially based on systolic/diastolic wall thickening and contrast enhancement of necrotic myocardium and fibrotic scar. Unfortunately, technical limitations of early scanners (poor sensitivity, competitively inferior diagnostic performance, and long acquisition times) relegated MRI for assessment of ischemic myocardial dysfunction to a research role for several years.

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