Abstract
Is this article by Cho and colleagues [1] just another paper on unsuspected or occult N2? In fact, the authors found occult N2 in about 1 in 10 patients with clinical N0. Occult N2 disease found at thoracotomy has been a source for an everlasting dispute between surgeons looking at locally advanced disease from different perspectives. In fact, arguments have been raised supporting the need for systematic frozen section analysis of mediastinal nodes during thoracotomy. Some have suggested that, should a positive N2 node station be identified, the resection is aborted and the patient sent for chemotherapy or for chemoradiation and only in the presence of complete response retaken back to the operative room.
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