Abstract
The basic disorder in acute gastroenteritis is the disrupted transport of water and electrolytes, to a different degree. The objective of these investigations was to evaluate the efficacy of two oral rehydration solutions (ORS) in the treatment of acute gastroenteritis in suckling piglets. Fifty piglets, 20 with acute gastroenteritis and 30 healthy controls aged 10 days were chosen at random upon the incidence of diarrhea, for one of two ORS treatments (ORS-1 and ORS-2). The piglets with diarrhea were administered a probiotic per os on the first day and an antibiotic parenterally, until the diarrhea disappeared. All the piglets were followed clinically from days 1-6 of the investigations. Faeces samples were taken for bacteriological culture on the first day. Clinical signs of hydration were better, as well as the difference in body mass of piglets with diarrhea under the ORS-2 treatment which was significantly higher (p=0.036) in comparison with the difference in piglets under the ORS-1 treatment. All piglets with diarrhea had normally formed faeces on the sixth day. Escherichia coli was isolated from faeces of 48 piglets. Piglets with acute gastroenteritis, treated with ORS with a higher osmolarity and which contained instead of citrate, bicarbonates in higher concentrations, with less potassium, more sodium and more chlorine had a better state of hydration, with a significantly bigger difference in body mass, and the results of their control group were not significantly different against those of piglets treated with ORS of a different composition.
Highlights
20 sa akutnim gastroenteritisom i 30 zdravih kontrola u uzrastu od deset dana, odabrano je metodom slu~ajnog izbora pri pojavi proliva, za jedan od dva ORS tretmana (ORS-1 i ORS2).
Prasad sa akutnim gastroenteritisom tretirana ORS, koja ima vi{i osmolaritet i sadri umesto citrata, bikarbonate u ve}oj koncentraciji, uz manje kalijuma, vi{e natrijuma i vi{e hlora, imala su bolje stanje hidracije, uz signifikantno ve}u razliku u telesnoj masi, a njihova kontrolna grupa nesignifikantno, u odnosu na prasad tretiranu oralnom rehidracionom solucijom druga~ijeg sastava.
Metodom slu~ajnog izbora odabirana su prasad na sisi koja su uklju~ena u ispitivanje dve oralne rehidracione solucije koje se koriste za rehidraciju dece sa akutnim prolivom (tabela 1).
Summary
20 sa akutnim gastroenteritisom i 30 zdravih kontrola u uzrastu od deset dana, odabrano je metodom slu~ajnog izbora pri pojavi proliva, za jedan od dva ORS tretmana (ORS-1 i ORS2). Prasad sa akutnim gastroenteritisom tretirana ORS, koja ima vi{i osmolaritet i sadri umesto citrata, bikarbonate u ve}oj koncentraciji, uz manje kalijuma, vi{e natrijuma i vi{e hlora, imala su bolje stanje hidracije, uz signifikantno ve}u razliku u telesnoj masi, a njihova kontrolna grupa nesignifikantno, u odnosu na prasad tretiranu oralnom rehidracionom solucijom druga~ijeg sastava. Metodom slu~ajnog izbora odabirana su prasad na sisi koja su uklju~ena u ispitivanje dve oralne rehidracione solucije koje se koriste za rehidraciju dece sa akutnim prolivom (tabela 1).
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