Abstract
It is wellknown that the majority of nonsteroidal anti� inflammatory drugs (NSAIDs) are ulcerogenic. Gel or ointment preparations of NSAIDs are free from this sideeffect, which is a prerequisite for the increase of aforementioned forms of NSAIDs. A major quality indicator of gels and ointments are rheological properties. Along with determining the quality of preparation, they influence manufacturing, expiration date and terms of storage. This article demonstrates the results of investigation of rheological indices of 3% gel preparation of diclofenac sodium such as plasticity, structural viscosity, and thixotropy. Obtained results confir m that the developed gel preparation has thixotropy, plasticity and is classified as a Bingham system.
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