Abstract

The conversion of butyrolactone into 4-methyl-5-(β-acetoxyethyl)thiazole has been thoroughly studied and modified so as to use the latter compound for the direct synthesis of thiamine (vitamin B1) via thiamine acetate. The main modifications are related to the stage of decarboxylation of α-aceto-α-chlorobutyrolactone. The results can be of interest for specialists engaged in the technology of vitamin B1.

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