INVESTIGATIONS AND SYNTHESIS OF SILVER-DOPED PHTHALIC ANHYDRIDE SINGLE CRYSTAL AND ITS EFFECT ON ANTIBACTERIAL ACTIVITY

Abstract

The objective of this study was to introduce phthalic anhydride into Silver, to produce a novel substance having biological activity. The Fourier Transform Infrared Spectroscopy (FTIR), Powder X-ray Diffraction (PXRD), Ultraviolet-Visible Spectroscopy (UV-visible), and antimicrobial analyses collectively yielded compelling evidence indicating the occurrence of chemical alteration in the crystal structure. The obtained materials had a remarkable inhibitory action against K. pneumoniae and S. aureus, resulting in almost complete suppression. Additionally, they also hindered the growth of S. epidermidis. The derivatives exhibited the highest level of antibacterial activity, indicating that the addition of phthalic groups resulted in the hydrophobization of Silver, thereby improving the interaction between these compounds and the constituents of the bacterial cell wall. The Fourier Transform Infrared (FTIR) analysis yields data about the functional groups present in a sample, whilst the Ultraviolet (UV) examination provides insights into its optical properties. The present study presents a novel approach to introduce dopants into single crystals of phthalic anhydride, so greatly enhancing their potential for environmental applications.