Investigation the effect of a magnetic field on the dose distribution of I-125, Ir-192, Yb-169, and Co-60 brachytherapy sources by Monte Carlo simulation

Abstract

Magnetic resonance imaging (MRI) during brachytherapy may alter the dose distribution of radioactive sources implanted in the tumor. This study investigates the impact of a magnetic field of 1.5 T, 3 T, and 7 T strengths on the dose distribution of high dose rate Co-60, Ir-192, and Yb-169, and low dose rate I-125 sources, using Geant4 Monte Carlo toolkit. After validating the simulation results by calculating the AAPM-TG43 dosimetric parameters, seven sources of each radioisotope were simulated in a water phantom, and their dose distributions were compared under the influence of a magnetic field. The simulation results indicate that using Co-60 brachytherapy under the MRI guidance is not recommended. Furthermore, the impact of a magnetic field of up to 7 T strength on the dose distribution of Ir-192, Yb-169, and I-125 sources is negligible, provided that there is no air pocket near brachytherapy sources.