Investigation on quality of life in patients with inflammatory bowel disease and their family members in Fujian Province

Abstract

Objective To investigate the quality of life (QOL) and its main influencing factors in patients with inflammatory bowel disease (IBD) and their families members in Fujian Province, and to provide an evidence for guiding the clinical strategy. Methods From September 2015 to March 2016, 114 IBD patients who met the standards, their 97 family members, and 113 irritable bowel syndrome (IBS) patients were enrolled. The QOL was assessed with 36-item short form health survey questionnaire(SF-36). T test, inspection rank and Chi-square were performed for statistical analysis in two groups and multiple group. The influence factors of QOL using multiple linear stepwise regression analysis. Results There was no difference in QOL scores between CD and UC patients ((62.82±18.55) vs (62.60±17.94); t=0.065, P=0.948). The QOL scores of IBD patients were lower than those of IBS patients (62.72±18.18 vs 67.25±16.26), and the difference was statistically significant (t=-1.975, P=0.049). The QOL scores of IBD patients with medical insurance were higher than those of patients without medical insurance (67.13±18.18 vs 57.06±16.68), and the difference was statistically significant (t=3.034, P=0.003). The dimension scores of body pain, general health, social function, emotional function, mental health in IBD patients relatives were lower than those of the general population ((72.29±17.27) vs (85.61±18.37), (60.92±17.08) vs (69.55±21.32), (80.80±15.32) vs (86.85±17.07), (68.38±37.38) vs (76.45±38.45), (61.97±15.30) vs (72.65±16.81), respectively), and the differences were statistically significant (t=-7.597, -4.979, -1.870, -2.125, -6.875, all P<0.05). The total QOL scores of families members of IBD patients with operation history was lower than those of without operation history (64.62±16.74 vs 73.98±14.15), and the difference was statistically significant (t=-2.540, P=0.013). Conclusions The QOL of IBD patients was lower than that of IBS patients. and also The QOL relates with payment types for medical care, and the QOL of family members of IBD patients also decreases. Psychological interventions should be in plemented in both IBD patients and their family members in clinical treatment. Key words: Inflammatory bowel diseases; Family members; SF-36; Quality of life