Investigation on in-stent recurrent stenosis after stenting of the extra-and intracranial artery in the elderly

Abstract

Objective To investigate the distribution of in-stent recurrent stenosis (IRS) after balloon-angioplasty and stenting in elderly cerebral ischemic patient and its correlative factors. Methods Totally 158 elderly cerebral ischemic patients with extra-and/or intracranial artery stenosis were treated with 172 stents in our hospital. The inhibition of platelet function was assessed by using the thrombus elasticity chart system in perioperative period, and the anti-platelet agents were adjusted correspondingly. 150 patients were followed up by digital subtraction angiography (DSA) and the other 8 patients were followed up by CT angiography, during an average follow-up duration of 8.3 months. Results There were 11 (6.4%) IRS lesions, among which 10 lesions were at the vertebral artery origin and 1 lesion was at common carotid artery bifurcation. 23.8% of IRS happened after vertebral artery origin stenting, and all in-stent recurrent stenosis were in the origin of non-dominant vertebral artery, whose IRS rate was 66.7%. Conclusions IRS are more common found in vertebral artery origin than in other parts of vertebral artery and are more common found in non-dominant side than in dominant side. Key words: Stents; Angioplasty; Carotid stenosis; Vertebral artery