Abstract
This study undertook the analysis of Cd, Cr, Mn, and Pb constituents in the various forms of five restorative preparations from ten GMP Chinese medicine laboratories. Collected samples of the commercial drugs were digested with HNO3-HClO4 in the presence of microwaving, followed by atomic absorption spectrophotometric analysis the results showed higher levels in the Mn content (27.9 ± 19.8 ppm) than Cr (2.86 ± 2.04 ppm), Pb (0.247 ± 0.578 ppm), and Cd (0.157 ± 0.167 ppm), based on the dry weight of the samples. The variation of heavy metal contents between laboratories, prescriptions, prescribed doses, and lot numbers may be attributed to the differences in the origin of raw materials as well as the additives used in the processing procedure. Comparison between prescriptions exhibited higher heavy metal contents (53.6 ± 24.7 ppm, the sum of Cd, Cr, Mn and Pb) in Kim-So-Ku-Gien-Wan. For purposes of safety and quality in Chinese drugs,it is necessary to confine individual heavy metal content on the basis of potential toxicity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
