Investigation on DOT guided FMT: Whether the FMT image quality is robust to the priori DOT information?

Abstract

The fluorescence molecular tomography (FMT) image quality could be improved significantly with reconstructed optical properties using diffuse optical tomography (DOT). However, different DOT algorithms and different constraint parameters usually lead to DOT images of obvious different image quality. In this paper, simulation experiment results demonstrate that the FMT image quality is robust to the great variation in DOT image quality.