Abstract

Morphology and minimum surface energy of Cu2O crystals effectively enhance the antibacterial activity. Minimum surface energy can be attained by controlling nucleation growth along with different Cu2O crystal facets. In this work, chemically assisted synthesis of Cu2O crystals in two unique morphologies, cube and octahedron, and their antibacterial activity against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) pathogens are reported. According to XRD data, the cube crystals that grew along the direction of the (111) plane offer higher antibacterial activity as compared to octahedron crystals. Interestingly, SEM images reveal that adding glycine during Cu2O synthesis alters its morphology from the cube to the octahedron. Both the Cu2O crystal facets exhibited antibacterial activity against S. aureus and E. coli which is well supported by surface energy and stability data.

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