Investigation of the spectroelectrochemical behavior of quercetin isolated from Zanthoxylum bungeanum

Jun Wang,Jianwei Jiang,Linxiang Liu

doi:10.1515/chem-2021-0031

Abstract

Abstract Flavonoids are common bioactive components in plants. Quercetin is the most abundant flavonoid in the human diet, accounting for more than half of the total daily consumption of flavonoids. In this study, adsorption and electrocatalytic activities of quercetin isolated from Zanthoxylum bungeanum on an electrode was studied via homemade electrodes. An in situ UV-Visible thin-layer spectroelectrochemical method was used to study the electrochemical behavior of quercetin in detail and to explore its electrochemical reaction mechanism. This experiment proves that UV-Vis thin-layer spectroelectrochemistry is a feasible way for studying the electrochemical reaction mechanism of flavonoids in plants.

Highlights

Zanthoxylum bungeanum is a kind of plant resource with high edible and medicinal value [1,2]
It can be seen from the figure that with the increase in the pH value, redox peak potentials of quercetin are negatively shifted, and the peak current tends to be smaller
When pH = 1.8, the system shows the best CV curve, with a good peak shape and large peak current. This behavior change may be caused by the hydrolysis of quercetin

Summary

Introduction

Zanthoxylum bungeanum is a kind of plant resource with high edible and medicinal value [1,2]. Quercetin, hyperoside, anisidine, arbutin, and rutin have been isolated from the pericarp of Z. bungeanum [5,6]. Excessive free radicals are harmful and can lead to changes in the cellular structure and the destruction of cellular functions, which may cause cancer, increased ageing, cardiovascular disease, and other health concerns. Excessive NO production in the brain can lead to neurodegenerative diseases. Quercetin can inhibit the production of NO in a dosedependent manner and shows a preventive effect on neurodegenerative diseases. The incubation of 10 mg of quercetin with the HepG2 cell line can effectively inhibit the binding activity of nuclear factor kappa B and protect against injuries induced by H2O2 [14,15,16]

Objectives

Results

Conclusion