INVESTIGATION OF THE SENSITIVITY OF SOME MICROBIAL ISOLATES IN DOGS WITH OTITIS

Abstract

Introduction.The article presents the results of the study of antimicrobial sensitivity of some isolates of the skin microflora of dogs with otitis. Methods. Methods of investigation included isolation of microbioal and fungal cultures, investigation of microbiological and biochemical features of isolates and investigation of their sensitivity to antimicrobials and antifungals. Results. A study of the sensitivity of Malassezia pachydermatis isolates on dense nutrient media showed that posaconazole was the most effective inhibitor of Malassezia growth, as evidenced by the obtained MIC50 and MIC90 values. Determination of sensitivity to antibiotics of representatives of the genus Pseudomonas showed that the most pronounced inhibition of the growth of microorganisms of this group was observed under the action of the following antibiotics: tobramycin, ceftazidime, marbofloxacin. Representatives of this group of microorganisms were also highly sensitive to penicillin group - ticarcillin, fluoroquinolones norfloxacin and ofloxacin, either to aminoglycosides amikacin or gentamicin. Discussion. Prospects of research are that further study of the sensitivity of microbial isolates of the skin to antibiotics, in particular causative agents of the cocci group, with further improvement of antibiotic therapy of animals suffering from otitis, especially in the presence of associations of causative agents of bacterial and fungal etiology.