Investigation of the Relationship Between Carbon monoxide Level, Amount of Cigarette Consumption, Cardiopulmonary Exercise Test and Pulmonary Function Test Results in Smoking Healthy Subjects

Abstract

Objectives: To investigate of the relationship between carbon monoxide(CO) level, cigarette consumption, cardiopulmonary exercise test and pulmonary function test results in smoking healthy subjects. Material and methods: Twenty-four male subjects(mean age, 22.67 ± 1.90 years) without any lung and heart disease were evaluated. Exercise testing was performed using the Jaeger brand bicycle ergometer. During the exercise test; blood pressure, peripheral oxygen saturation(SpO2), dyspnea and fatigue severity(Modified Borg scale), maximal load, RER, maximal heart rate were recorded. With the device named Breath Carbon Monoxide monitor CO levels were measured. Pulmonary function tests were performed with spirometer. Results: The average CO was 20.71±5.26ppm, the amount of cigarette consumption was 7.45±3.22 packets×years. There was a correlation between the CO and the amount of cigarette consumption(r=0.60, p=0.002). There was no relationship between CO and pulmonary function test results, but there was correlation with RER(r=-0.47, p=0.02). During the exercise test heart rate, blood pressure, SpO2, severity of dyspnea and fatigue increased(p Conclusions: Although younger smokers were not affected by respiratory function, hemodynamic stresses were increased as a result of exercise test depending on the cigarette consumption. The measurement of CO, which is objective measurement, reflects the cigarette consumption. We think that CO measurement should be considered in interpreting the exercise test results of healthy young cigarette smokers who have not yet deteriorated their respiratory function.