Abstract
Aqueous leaf extract of the mistletoe was investigated for hypoglycaemic and hypocholesterolaemic effect in diabetic rabbits. Diabetes mellitus was induced in rabbits in groups I-II by a single intraperitoneal injection of alloxan monohydrate at 100mg/kg body weight. Following confirmation of hyperglycaemia, groups I and II were treated with the extract at 1.32 and 2.64g/kg body weight for three consecutive days. After the last treatment, rabbits were fasted for 12 hours and bled at 0, 2, 6 and 24 hours. Serum glucose levels were determined by the glucose oxidase method and cholesterol levels by Liebermann-Buchard method. The results showed statistically significant decreases (P 0.05), when compared to control group III. Aqueous leaf extract of the mistletoe (an epiphyte of lemon trees) may be recommended for frequent consumption in the management of insulin-dependent diabetes. Keywords : Mistletoe Extract, Glucose, Alloxan-Induced Diabetic Rabbits Journal of Medical Laboratory Sciences Vol. 14 (1) 2005: pp. 28-32
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