Investigation of the distribution of the prevalence of albuminuria in community elderly population in Tianjin

Abstract

Objective To investigate the distribution of the prevalence of albuminuria in elderly population of a community in Tianjin and analyze the situation of their early renal injury and its clinical and environmental risk factors. Methods The morning spot urine sample and the clinical data from 2 050 old population(aged ≥60 years)who took part in healthy examination were collected.The concentration of urine albumin and creatinine were tested, and the albumin/creatinine ratio(ACR)was calculated.We analyzed the prevalence of albuminuria, and used logistic regression to analyze the odd ratio(OR)of risk factors. Results In the 2 050 participants, the prevalence was 1162 cases (56.69%) for hypertension, 264 cases(12.86%) for diabetes and 568 cases(27.71%) for albuminuria.The prevalence of ACR>30 mg/g was lower in men than in women(21.61% vs.32.55%, P 80y old people.The OR of increased ACR was 2.03 in >80y old people after adjusting gender.Body mass index and waist circumference were not the risk factors of increased ACR after adjusting confounding factors.There was an association between the prevalence of albuminuria and triglycerides(OR=1.19), hypertension(OR=1.68), diabetes(OR=1.95). ACR value was increased along with increased number of cigarettes, however, there was also no association between smoking and albuminuria(P>0.05). Physical activity could reduce the risk of albuminuria, the OR of ACR>30 mg/g in those undertaking a activity once daily was 0.52(P=0.027) Conclusions There is a high prevalence of albuminuria in elderly population(higher in female than in male)in a community of Tianjin.Hypertension and diabetes have the greatest influence on ACR.Additionally, the physical activity once daily can reduce the risk of albuminuria. Key words: Albuminuria; Risk factors