Investigation of the Administration Accuracy of an Auto Infusion Device in <sup>18</sup>F-FDG PET

Abstract

Purpose The administration accuracy of the automated infusion device for the positron emission radiopharmaceutical affects to calculation of the standardized uptake value (SUV) in 18F-fluorodeoxyglucose (18F-FDG) PET examination. The purpose of this study was to investigate the administration error in the clinical use of an automated infusion device for quantitative management in PET examination. Methods We assumed clinical use of the automated infusion device and investigated two types of administration errors. First, for investigating the administration error over time in a day (errorday), a total of 13 infusion works were performed every 30 minutes. Second, for investigating the long period administration error (errorperiod), the infusion work was performed once before clinical use of an automated infusion device. The dispensed radioactivity was set to 150 MBq. The administration error was calculated using output values from the automated infusion device and measured values from the dose calibrator. Results The administration errorday was 0.9±1.3%, and the maximum error was 2.7%. The administration errorperiod was 1.1±2.0%, and the maximum error was 5.9%. Conclusion We investigated the administration error of the automated infusion device. We confirmed the approximately 1% administration error and high-accuracy injection in an automated-device method.