Investigation of Serum Trace Element Levels of Nigerian Women at a Late Stage of Pregnancy

Abstract

Abstract Introduction: Minerals such as selenium, zinc, copper, and manganese often referred to as antioxidant trace elements have been recognized as modulators of oxidative stress-induced conditions. Due to this very crucial function, their constant monitoring during gestation is not only encouraged but desirable. Aim: The study aims to evaluate serum levels of Zn, Cu, Mn, and Se during gestation. Materials and Methods: Forty third-trimester pregnant women (29 weeks to term) attending antenatal clinics at maternity centers within the Osogbo metropolis as well as 40 apparently healthy women, age matched, and nonpregnant that served as controls were participants for the study. Serum obtained from 5 mL of blood was used for the elemental study (inductive computerize plasma emission spectrometry). Data were analyzed using Student’s t-test and Pearson’s correlation coefficient. The level of statistical significance was P < 0.05. Results: Concentrations of serum trace elements (Zn, Mn, and Cu) levels were significantly lower, but selenium was significantly higher in pregnant women compared to the control group. Correlation results revealed a relationship only between copper and manganese. Conclusion: The results of this study showed that Nigerian pregnant women in the Osogbo metropolis are at risk of zinc, copper, and manganese depletions. This suggests that both the fetus and pregnant mother may be susceptible to oxidative stress-induced conditions.