Abstract
The present study was conducted to evaluate the total internal intake of pyrene and estimate the relative contribution of air to total absorption rate of this compound in Shiraz, Iran. Sixty ambient air samples were collected every 3 days at two stations to measure particulate-bound polycyclic aromatic hydrocarbons (PAHs) including pyrene. Urine samples were also collected from 120 primary school students to determine 1-hydroxypyrene, as the solely biomarker of pyrene. The total pyrene intake and estimating the relative air contribution in total intake were modeled using concentrations of particulate-bound PAHs and 1-hydroxypyrene levels. The mean total intake of pyrene for students lived in urban and suburban areas were 5.30 and 4.31 μg/day, respectively. The relative contribution of ambient air to total pyrene intake was 0.88% and 0.71%in urban and suburban areas, respectively. The findings indicate that ambient air in Shiraz is not a major source of exposure to and intake of the pyrene.
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