Abstract
To determine the relationship between use of oral contraceptives and thromboembolic disease 58 married women aged 16 to 40 years discharged from 19 hospitals near London with diagnosis of thromboembolic diseases (ICD 463-466) without predispoition were interviewed. 116 married controls unaffected by these diseases were matched by hospital admission date age and parity. The controls differed in lower incidence of previous thromboembolism lower weight less heavy smoking. Of 58 affected 26 (45%) were using pills within the month prior to illness and among 116 controls 10 (9%) were using pills yielding a relative risk of 9. In a small sample of 9 patients with cerebral thrombosis 5 were using the pill. Of 13 women with coronary thrombosis none were users.
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