Investigation of postoperative satisfaction of facial autologous fat grafting with platelet-rich plasma

Abstract

ABSTRACT Objectives: This single-center prospective, case-controlled study investigated satisfaction and esthetic results as rated by the physician and patient, respectively, by following up thirty patients with aging face, who underwent facial autologous fat grafting with platelet-rich plasma (PRP). Materials and Methods: A retrospective review of thirty patients, who were suffering from facial sagging or partial depression and requiring autologous fat grafting between February 2012 and September 2015. Photograph was taken before and 3-month after the operation. Patient and physician satisfaction was rated using visual analog scale (VAS) ranging from 1 (least satisfied) to 10 (most satisfied) 3 months after the operation. Statistical difference between the patient and physician satisfaction scores was analyzed by SPSS 17.0 software. Results: The patients' average age was 34.5 ± 1.2 years. The average VAS score of physician satisfaction was 7.9 ± 1.0, and the average VAS score of patient satisfaction was 8.0 ± 1.2. There was no statistically significant difference between the two groups in scores (P = 0.859; P > 0.05). Conclusion: There is no evidence that different donor sites or different donor-site preparation will lead to different outcomes. Multilevel injection is recommended for autologous fat injection. The high satisfaction scores indicated a good esthetic result of facial autologous fat grafting with PRP. Autologous fat as one of the popular soft tissue fillers is durable and safe. The biggest challenge is the high variation in absorption rate. PRP may lead to higher survival rate of fat and satisfaction level. The stability of survival rate of autologous fat grafting with PRP and the connection between complications and PRP technique need further study.