Abstract

With the help of Raman spectroscopy method the protective action of Semax on free radical lipoperoxide oxidation of non-saturated fatty acids of external amphipatic phospholipid layer of low density lipoprotein (LDL) of blood serum of rats at ischemic insult is investigated, that allow one to make the conclusions about degree of oxidative stress in brain tissues at action of Semax at this pathological condition. By estimation of damage of LDL it is shown that Semax decreases the oxidative stress in brain tissues at ischemia. Lipoperoxide oxidation of LDL of blood serum can be used as marker, determinating the level of oxidative stress in brain tissues at ischemic insult that can be used in clinical practice.

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