Abstract
Wheat bran has been consistently reported to protect against colon cancer. To investigate the mechanism of the unique characteristics of wheat bran, the morphology and zeta potential of micro-particles released from wheat bran and sugarcane bagasse fermentation by human faecal flora were studied by atomic force microscopy and laser light scattering technique, respectively. Microparticles released from wheat bran fermentation differed significantly from those produced from sugarcane bagasse fermentation in shape, size (237 VS 454 nm), and zeta potential (-20.01 VS -3.96 mv). Scanning electron microscopic observations showed that the structure of fermented residue of wheat bran was more loose and porous than that of sugarcane bagasse, and had a larger surface area. In vitro studies revealed higher binding capacities of fermented wheat bran for bile acid, cholesterol, and peanut oil compared with fermented sugarcane bagasse.
Highlights
Dietary fibres may prevent or promote colon cancer [1]
Size distribution, and zeta potential of the particles released from wheat bran and sugarcane bagasse fermentation by human faecal flora
atomic force microscope (AFM) and zeta potential measurement are quite suitable for investigation of micro-particles released from wheat bran and sugarcane bagasse fermentation by human faecal flora
Summary
Dietary fibres may prevent or promote colon cancer [1] Their preventive effects have been ascribed to the production of short-chain fatty acids (SCFAs) during fermentation in the colon [2]. The charge density, molecular weight, and structure of carbohydrates are important factors that influence these processes [6]. Some of the possible mechanisms proposed include: carcinogen binding [1]; reduction of the exposure of colon epithelia to carcinogens by increasing stool bulk and decreasing intestinal transit time [9]; and antitumour effects from phytic acid, antioxidants, and lignans in wheat bran [10,11,12,13]. Rice bran contains more phytic acid than wheat bran, the latter seems to be more active in preventing against colon cancer
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
