Investigation of Metabolic Parameters of Women of Reproductive Age

Abstract

Objective: Fertility rates are decreasing every year, mainly due to socioeconomic and medical reasons. In this study we aimed to investigate the incidence of metabolic disorders that may negatively affect reproduction. Methods: Glucose parameters of 5892 patients, lipid parameters of 2491 patients and thyroid function tests of 457 patients were retrospectively examined. Patients divided into two groups in terms of age. Each age groups were divided into subgroups as diabetic, prediabetic, non-diabetic and euthyroidism, overt hypothyroidism, subclinical hypothyroidism and hyperthyroidism. Results: The rate of Euthyroidism was 85.8%, overt hypothyroidism was 4.2%, subclinical hypothyroidism was 3.5%, and hyperthyroidism (subclinical+overt) was 6.5% in all ages. There was no significant difference in st3, st4 and TSH values according to age (p values p = 0.051, p = 0.195, p = 0.585, respectively). The rate of diabetes was 4.7%, non-diabetes 83.7% and prediabetes was 11.6%. There was a significant difference between diabetic, prediabetic, and non-diabetic according to age (p≤0.001). Conclusion: Thyroid dysfunction and glucose metabolism disorders are more common in our country due to genetic and environmental factors. Early diagnosis is very important to avoid the unwilling side effects of this condition. For this, new approaches are needed, such as close follow-up clinics aimed only at women of reproductive age.