Abstract
Abstract As an alternative to optical flow cytometry, magnetic flow cytometry has emerged in recent years for single cell analysis with sheath-less flow conditions. Instead of measuring scattered light, magnetic fields of magneticallylabeled cells are recorded and analyzed. To determine microfluidic opportunities to manipulate cell trajectories for in-situ cell focusing we use mechanical guiding structures and magnetophoretic forces. A 3D-microfluidic particle simulation has been implemented that revealed parameters ensuring the crucial balance between hydrodynamic drag and magnetophoretic forces. Experimental measurements verified the 3D particle tracking simulation.
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