Abstract

The limited view of a planar detector array results in artefacts in the reconstructed images. To address this, iterative image reconstruction methods have been proposed. However, there remains a need for a rigorous assessment of their performance in terms of artefact reduction, small structure detection, spatial resolution and robustness to noise. Additionally, an understanding of the impact of regularisation parameters on image fidelity and SNR as a function of the target geometry and instrument noise is required. The aim of this study is to explore these factors and advance the practical application of iterative reconstruction methods for in vivo images acquired using a planar detection geometry.

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